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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd61561cb8e7198cef0e37f0c15e3fad07e2a94f920c2fc3282c25c35bf4fafcb' 
  AND token = 'UJMCVC5+tjgWDpSWd0IiLcQMCAH5QgZZ4Qgio6G1wjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}