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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cea69b1d2c723c165b1114599385f2e7d002d35d03ffbe1fe82a3a67c21b8e8' 
  AND token = 'el8MbS/YOsevov128oIrmsfFiJg0QwjyBmBcLGJ5cJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}