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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49240fefef1ec3f88812fe99f44647668d8c95b774a8fe6254e74201bbce485e' 
  AND token = 'WnQ2ZrS6CVL6DXyqvt5f/jWVqDTUGXZVL5/sZ7qumVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}