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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27c5f2a8e2bd1a6f25f525554c9538aa901b9d07eed202bf46a28fcde02b5d8' 
  AND token = 'fCHbiF3+ctdwfAOHUdXuBO1mj/wQOSULj2yWNnp08dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}