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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8964dbc68a4e4d80e2d3637e3215a01eba0ecd263c930a3a4301fb8f9c389e' 
  AND token = 'YeaQNcUMJ10LijPN6W/xgs9z5vQihwH+BW9rOWGy3N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}