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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bc83034b14afbad14d4e921aca2c7e20f6a905b8b698db5b87915e93848d79' 
  AND token = '4NEUlx02x9HW/KOMIbUG9GfOgbt53oyvL40IgTUL55w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}