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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53ef0785b3b7cc43ec85d68f2293fbd458ea24826cb4099ea3eb48095ef105c' 
  AND token = 'f5rfphXQTEsi0bAw5Cuwx7TABqCCcgCWWaad/OG2Z0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}