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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4f03727c034bed541081a484e1d145543e89f3e2b771ae3e9618bb1f05c909' 
  AND token = '3Z4S2QPa87wj+0cldEVHtR88HlMCWCCHz9AzSpsymgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}