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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0be24aca2368d6ab6ff280cf99a2da9498e1e08519a767c7a8f1513831e7cf' 
  AND token = 'iJoBsr3xfkX0FmBTRiqy+LRy4A3m7Z/LchytMnh24bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}