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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278ea09cc50248bf64f4a0b3312cd2fc415d45630a363b9f3702189f7db57319' 
  AND token = '+j2hk3AAzmjELNQrS1rgldktZecyF9nqgNGOG5xbq2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}