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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f91308d70ac45540e23758130ec7618a7599b5655d8732f9fa8b3d030d2b1b' 
  AND token = '5Z0pUtN57EEHuRHAKI+N4HG4SdiZtHAIMU7HbuZNQdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}