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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51085276de8c9892b322764fa1d21b89fba709eca868e460ed2569e378b1ed1c' 
  AND token = '4DhhcJ4q1/iIanvd3zlhmuxPSbd+NgyWNP+1ViFeTF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00225

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}