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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a7d1728da5f19675066fdef34b484a63d079bc598f995c6dcd669e08196526a' 
  AND token = 'ZsXB/pntfa9px6TUeyzFH91qlNVUuErAzXdm7THw7bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}