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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05d7968da3875d8ba0474970069cf7cf6d900076b3d98d8b838a4fc83b00d86' 
  AND token = 'jRcEDmFi+7sTAXINgmVqFywpJMEgBjMM3EFD1TeS/xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}