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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8224104d10bc5d82b89933f280fe0fc96be9bf1b53768b71f515371174d495ff' 
  AND token = 'EB532OkID/7Sc4iTC5WXGA3gtDjX0DIq7B6CO7YAj4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}