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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ac4e687f7808688f1a074117e932e32503ea32b364646e21cd3f6caa08451a' 
  AND token = 'iMk1WqBwk9YJEejks5YwJERjMU3tYnIHyDUwarPTeR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}