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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42af5b848560167dab0b14012bbedbb26ba5a10872d962406d5780bc427ed391' 
  AND token = 'Rzn+64704c+txM8/0MJ1enu9a7XmrIbAM4QMWmrJHQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}