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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9082682c366fd3c4ee45279092645db7e1a9c00f5d75143d0cd0bda6700d1e2f' 
  AND token = 'fxVZ/0xKDrjWqFmHkgZPxESE4/15Aju8vVtnIKrK46A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}