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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4ca441c39a98ef9e6a29da9220b2815179b1455c50904fe2d5c1649d511af3' 
  AND token = 'z7B3u7SC00lt0YDOyUfCg66dPT70V8mm6ELdRWKoE5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}