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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b537806ae72cd21db350ff2e0c9812dc9b6df36b136b88e27a10dd563902221' 
  AND token = 'i2fYXNdWIfGOo3gORieeBD4u2m9wb3R0B4kM0UW8ub8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}