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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b88d4c7699854bcc9e1e5c8767b3616c3f36c7d5f9add9aa8c879db10e680b' 
  AND token = 'kQqO2l4L4hjp2jLTQLK5y3DSjFQV4d/ekD9tMdZXWaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}