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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b370c701849865974a18e2d64040a558a02079f67042412bda636a0285a7af6' 
  AND token = '6z0lEyTBvhrbMScLXoNs+yWnGcCImASJ1rEoed7lk00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}