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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c8d37bc1512fffde061e7df9f95ed5cea5b689510e2a9ca78161b1d64c8625f' 
  AND token = 'IYmeoJRnf3vr7w3wk+gCZAc2NdVDDD2HJVuy7JiWdXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}