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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9421fac8b5285b8662e66eb986391b8c7f31a08e26f397a08bcd4bd728f9ce' 
  AND token = 't/rOEpkjvi9OGuU+c8nfCiVYSQhv/bffL6AQaez3H7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}