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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8e24787085fb61e239311b3c710dea453ed4ccc533bd755a9610a8e3b005d8' 
  AND token = 'fl7sNFv0OjBtr69PjST/vDJBTs7ug7Z3cG/xOnJk2Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}