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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165f512f61a91c5a68f05212afee58bccb444442841280bd76bce6e1222fe017' 
  AND token = 'kn/9pmyA4EkMtHn8eM2tmn71Xitm9X4wO3OebzU2pWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}