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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0811271da852e240e4a801ba7afd95b63c0b0f20936fb04dbfc3f8cc806f1a76' 
  AND token = 'TMyjcoP1QfZpTEYheKotcLDAtbGAItlTqS1djGp7i2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}