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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac10a9cbe75787a3868cdbaa4f6838285abd47a4a2320249292e3727eb6dd751' 
  AND token = 'NvZWG+43soI8RzcyE5h9mqArEw1XvYKtU8sycn+89cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}