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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ebb50fbe5a321e9bd5d55167ad188bd89627d6abb7f0ac23e0d8fda0fb3183f' 
  AND token = 'SVQ5k4fc2mHAyy6QSNNHNg2L6c8pUX3RCrk/TSKx7/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}