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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e6e10942ab423514037e951104ffc24ff949639f7b5aa0303b5ac3e9ff846c' 
  AND token = 'dMOyoA9RT13eJtO64D8P7Zfc20MSbs+32ObZspJ1HR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}