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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1e4245444f1a76d686d021e8a74f6df073cd2d05112f583583fe4e03175d47' 
  AND token = 'huMwBC+2aE8v7u41cc382k50TbSEl9McnkNvRp8NQbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}