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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6852266065941b32c05441b2dc674b62304f5cb24af1f45fdc28a24fd4eaa5ca' 
  AND token = 'FfLWwi/DRYl6PLgmMDGbt1bIoR6T1SOmz7vtolGN0Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}