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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e09745a7522b7043b72c60425963c10259d2f7e9f87ace32e4c8cc53bb406e74' 
  AND token = 'yKgCqgDZYhoZ/nV4kBmRmu1tWWs3Sy/NDJn1Par4YTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}