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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd320835abb3a765a5b0323acb35009ab1cfa5219baf88b9841ac8bb3c8b49668' 
  AND token = 'Sq0v2Vnm4Z8+/OH/s83TpyfCgFRZdPpi2Tl+xJF1hcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}