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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81671a2e20f8b14e94fd2c5d8185f43f1751ca42f1d3af71d46204940acb5d43' 
  AND token = 'HOELnR3ud24CtPvfYL97CKHirR7GtSWMPrExUkh2MjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}