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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53548228ffc70d133d5be0363374de905b799d2bee71690ce00e91eb7eacbb04' 
  AND token = '1UJsoBbSbcCdh34ZF3gdzRwomG8YTCnPhQyaqKChXL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}