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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f8170fb02fe98c93e07f7d673e25e5b09bc90981da6aadde1fe4a453f91404' 
  AND token = '8FLtu/DsRliSbGAbAQbs/DhzvbUgKfH9Zxm+FNZXlak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}