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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad23b675b25e3f3ad38f75f345b736802750c074e4542d9ebaef8940333616c3' 
  AND token = 'hOw1agpHGOR6d1ZC+73CfyyG9S6+ANJRo0zVsLB62rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}