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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c85137362a72b81fe9669eb7f24f966fdf2b1163ba46587f9a85907123f8a6' 
  AND token = '2phS7b8rgmqJ9oYUz9OqwOUW0Pj13iz+bw0Xdfv1bAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}