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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ea538ec7a0866f5766fcb760c706be50d12e09337ececb8aacab3ce0b057f9' 
  AND token = 'H6Gj4Rq/04aYyAJMR5hGspHSHIFy+Bf8rXteuOVEAGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}