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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4944fa1fb1c2c7f3ea0601fc4835993dcf3c1622922496f545a4c7c2ddac18' 
  AND token = 'cFD1ZjktTy9QxcpsZFcwCoUjrjs1kYLMxLS+WLAttRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}