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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e08115f0d3a19c16b5157e297292127c23eb55a09dd078bfe73c41c6e4e13c' 
  AND token = 'wxxWVR9rBEDLxfZg/d4cq4qHOHI2Q06arfb3ZlL6Cg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}