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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921fe43c9e0a9a489dab8c5daeb13a16274a23eba14e830b17845ffe5f55a3b6' 
  AND token = 'WEW0nFA5Ju1AgOIB5XP2aoBO1EUqI/IHHJARADH/5bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}