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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c830596680e931a4927f3c04b8a03a5fe30783e324a45cea365c3d8a885bd3' 
  AND token = '/NKk4Wb/JYk3mcQW24mKVpR1/2T9zTTjfSFKoeNxDwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}