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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccfc51929adb87aede33c0fd95c7c9247d6e8fa9a592015e2413fc2cbef1b086' 
  AND token = 'cwQ4E70TPMdcQh2/8g/PLz/CHtve4ucbf23hUxQ8i4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}