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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1f4195e61817f034817c5d03eb9361e9ca9515aa5cfec9ba0ea27984ce8160' 
  AND token = '7EEQQ+vXUPQNKd982+2nHQJuKpAur6sKU5fJm0qCHFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}