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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '603cb5851c95a33deb98868936897a0201de6cf823de52259f5d3e6cc2b1ca1f' 
  AND token = 'OyAhwZHq7atWSmb7/w+f39UXL4sv36YYJRHtYNdXuJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}