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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed48eb82d132e2fc1217203294dba9175945d8899d463046676ce2bc695c3b9f' 
  AND token = 'x0UDMG+L2WJO+zOjJ/SeADeppzJiGUISOPpznmHvnC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}