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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ff4fa0e63d96d9bd027401f4d1c668c5a2d8ae798a73e7b72e7e9778281daf' 
  AND token = 'l2OXBvyyl6/ouU08Qb+LOV96DQZmYRh02lIXL29iBM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}