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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca21360c6017d61002eff3456c367658c23d06d21a446b1a4b19dfd04cea2b6' 
  AND token = 'HnAR6gIR6TzVDWnsFOohO1BijMN2TEF2GVRVk6d4lCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}